Priapus Shot® (P-Shot®)

Dr. Leonardo now offers the Priapus Shot® (P-Shot®), one of the latest treatment methods for Erectile Dysfunction (ED) and Peyronie's Disease. It was developed from Platelet Rich Plasma (PRP) Treatments, a way to stimulate the body to heal, repair, or regrow various tissue using platelets, growth factors, and other chemical markers processed in high concentrations from the patient's own blood. For more information, read about Regenerative Injection Therapy. The P-Shot is a nonsurgical option to strengthen erections. Patients who have had success with Viagra and Cialis may no longer need those medications or will require a lower dose. There is more spontaneity when the mood strikes to be able to achieve firmer erections. The penis is rejuvenated as more blood vessels and penile tissue develop from the procedure. Patients get all the benefits of improved erectile function without unwanted side effects, the risk of drug interactions, and minimal to no recovery period. Patients have also reported a 10%-20% increase in girth and length, but results will vary. Girth is gained first, followed by length. Smokers will have inferior results as smoking is detrimental to circulation.


If you wish to be treated, the P-Shot® Procedure steps are as follows:

  1. Physical Examination.
  2. Application of a Topical Local Anesthetic to achieve numbness/comfort during the procedure.
  3. Withdrawal of 60mL of blood.
  4. Centrifuge of Blood Draw.
  5. Harvesting of injected components, a total of approximately 10mL of highly concentrated platelets, growth factors, chemical markers, and serum.
  6. Activation with Calcium Chloride.
  7. Release of growth factors from the platelets into the liquid of the tube.
  8. Injection of the liquid into the penis using the smallest gauge needle available.
  9. Application of vacuum cylinder for 10min.
  10. Discharge instructions provided.


You may experience mild soreness and slight bruising, but you may resume regular activities as tolerated. Many patients return to work or even proceed with their usual exercise routines. If the mood strikes, you may engage in sexual activity afterwards. Intercourse is allowed but bear in mind the penis has puncture wounds that need to heal. Before that, there is risk of transmission of blood bourn illnesses. We recommend practicing safe safe for a period of 1 week.


Assuming the P-Shot is successful in restoring firmer erections, the results may last up to 12-18 months. Results may vary though, especially in smokers, as smoking interferes with circulation. Some patients may require a second treatment after 4 to 5 months to achieve firmer erections. Those with Peyronie's Disease will require a series of 3 treatments, one shot every 6-8 weeks.